Hepatitis B virus-like particle: targeted delivery of plasmid expressing short hairpin RNA for silencing the Bcl-2 gene in cervical cancer cells

Gene therapy research has advanced to clinical trials, but it is hampered by unstable nucleic acids packaged inside carriers and there is a lack of specificity towards targeted sites in the body. This study aims to address gene therapy limitations by encapsidating a plasmid synthesizing a short hair...

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Bibliographic Details
Main Authors: Akwiditya, Made Angga, Yong, Chean Yeah, Yusof, Mohd Termizi, Abdul Razak, Mariatulqabtiah, Ho, Kok Lian, Tan, Wen Siang
Format: Article
Language:English
Published: Multidisciplinary Digital Publishing Institute 2021
Online Access:http://psasir.upm.edu.my/id/eprint/97514/1/ABSTRACT.pdf