Abrogation of oncogenic k-ras function by andrographolide derivatives via in silico, in vitro, and in vivo approaches
The rat sarcoma (Ras) proteins are small guanosine triphosphatases (GTPases) that act as molecular switches in major signalling pathways involved in cell proliferation, differentiation, and survival, such as mitogenactivated protein kinase (MAPK) and phosphatidylinositol 3-kinase (PI3K) cascades...
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| Format: | Thesis |
| Language: | English |
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2021
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| Online Access: | http://psasir.upm.edu.my/id/eprint/97712/1/FPSK%28p%29%202021%2015%20-%20IR.1.pdf |