An Expedient Synthesis, Acetylcholinesterase Inhibitory Activity, and Molecular Modeling Study of Highly Functionalized Hexahydro-1,6-naphthyridines

A series of hexahydro-1,6-naphthyridines were synthesized in good yields by the reaction of 3,5-bis[(E)-arylmethylidene] tetrahydro-4(1H)-pyridinones with cyanoacetamide in the presence of sodium ethoxide under simple mixing at ambient temperature for 6–10 minutes and were assayed for their acetyl...

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Bibliographic Details
Main Authors: Almansour, Abdulrahman I., Kumar, Raju Suresh, Arumugam, Natarajan, Basiri, Alireza, Kia, Yalda, Ali, Mohamed Ashraf
Format: Article
Language:English
Published: Hindawi Publishing Corporation 2015
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Online Access:http://eprints.usm.my/38309/1/An_Expedient_Synthesis%2C_Acetylcholinesterase_Inhibitory_Activity%2C_and_Molecular.pdf