The role of HIF-1α and VGSCs in influencing metastasis of breast cancer cells

The role of HIF-1α as well as CBP and p300 in the regulation of VGSCs particularly the isoforms Nav1.5 and nNav1.5 which are highly expressed in aggressive breast cancer cells has yet to be explored. This study was designed to investigate the role of HIF-1α/CBP/p300 in the regulation of Nav1.5 and n...

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Bibliographic Details
Main Author: Dewadas, Hemaniswarri Dewi
Format: Thesis
Language:English
Published: 2018
Subjects:
Online Access:http://eprints.usm.my/56804/1/Hemaniswarri%20Dewi%20Dewadas-OCR.pdf