The role of hypoxia in controlling Volatagegated Sodium Channels (VGSCS) induced breast cancer invasiveness

This study was designed mainly to investigate the role of transcription factor, hypoxia inducible factor- 1a (HIF -1a) in enhancing Nav1.5 and nNav1.5 expression in breast cancer that transforms it to become aggressive. siRNA was conducted to knockdown HIF -1 a expression in the aggressive MDAMB-...

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Bibliographic Details
Main Author: Makhtar, Noor Fatmawati
Format: Monograph
Language:English
Published: Pusat Pengajian Sains Kesihatan, Universiti Sains Malaysia 2016
Subjects:
Online Access:http://eprints.usm.my/57499/1/DR%20NOOR%20FATIMAWATI%20MAKHTAR-Eprints.pdf