The effect of Trichostatin A (TSA) on the regulation of Voltage-Gated Sodium Channels (VGSCS) expression by Repressor Element 1 (RE-1)-silencing transcription factor (REST) using MCF-7 human breast cancer cell line
The repressor element 1 (RE-l)-silencing transcription factor (REST) mediates the repression of several neuronal genes in non-neuronal cells. REST represses its target gene through histone deacetylation, chromatin remodeling and methylation. Voltage-gated sodium channels (VGSCs) especially the ne...
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| Format: | Monograph |
| Language: | English |
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Universiti Sains Malaysia
2014
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| Online Access: | http://eprints.usm.my/57830/1/NOR%20IZZATY%20BINTI%20MAS%20SUDIN%20-%20e.pdf |