Evaluation of genetic alterations of IDH1, TP53 and CASP9 genes as biomarkers in glioma patients
Isocitrate dehydrogenase isoform 1 (IDH1) hotspot mutations are commonly found in gliomas, especially in low-grade gliomas and secondary glioblastoma. The IDH1 p.R132H (c.395G>A) gathered a significant association with clinical outcomes in previous literature. The p53 pathway is usually dysreg...
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| Format: | Thesis |
| Language: | English |
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2022
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| Online Access: | http://eprints.usm.my/58578/1/PUA%20JING%20YIT-24%20pages.pdf |