Discovery of novel Coumarin-Schiff base hybrids as potential acetylcholinesterase inhibitors: design, synthesis, enzyme inhibition, and computational studies
To discover anti-acetylcholinesterase agents for the treatment of Alzheimer’s disease (AD), a series of novel Schiff base-coumarin hybrids was rationally designed, synthesized successfully, and structurally characterized using Fourier transform infrared (FTIR), Nuclear magnetic resonance (NMR), and...
Main Authors: | , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI
2023
|
Subjects: | |
Online Access: | http://eprints.utm.my/106207/1/SyazwaniItriAmran2023_DiscoveryofNovelCoumarinSchiffBase.pdf |