Molecular dynamics simulations reveal the inhibitory mechanism of withanolide a against α-glucosidase and α-amylase.

Diabetes mellitus (DM) is a global chronic disease characterized by hyperglycemia and insulin resistance. The unsavory severe gastrointestinal side-effects of synthetic drugs to regulate hyperglycemia have warranted the search for alternative treatments to inhibit the carbohydrate digestive enzymes...

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Bibliographic Details
Main Authors: Oyewusi, Habeebat Adekilekun, Wu, Yuan-Seng, Safi, Sher Zaman, Abdul Wahab, Roswanira, Mohd. Hatta, Mohd. Hayrie, Batumalaie, Kalaivani
Format: Article
Published: Taylor and Francis Ltd. 2023
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