Lead structures for applications in photodynamic therapy. Part 2: Synthetic studies for photo-triggered release systems of bioconjugate porphyrin photosensitizers

Photodynamic therapy (PDT) selectivity and specificity can be improved by binding the photorsensitizers to target receptors. One approach is to cross-link porphyrins to a biological target receptor via the photocleavable o-nitrobenzyl linker, where a controlled released of the porphyrin can be monit...

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Bibliographic Details
Main Authors: Bakar, Mohd. Bakri, Oelgemöller, Michael, Senge, Mathias O.
Format: Article
Published: Elsevier Ltd. 2009
Subjects: