Rational approach to the selection of conditions for diastereomeric resolution of chiral amines by diacid resolving agents
This paper presents an experimental and modelling approach to understanding the key conditions for diastereomeric resolutions of chiral amines by diacid resolving agents. The model is used to calculate resolution yields and enantiomeric excesses on the basis of acid–base chemical equilibria, forma...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2006
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| Subjects: | |
| Online Access: | http://eprints.utm.my/3108/1/Nazlee_Tetra2.pdf |