alpha-Mangostin from Cratoxylum arborescens demonstrates apoptogenesis in MCF-7 with regulation of NF-kappa B and Hsp70 protein modulation in vitro, and tumor reduction in vivo

Cratoxylum arborescens is an equatorial plant belonging to the family Guttiferae. In the current study, α-Mangostin (AM) was isolated and its cell death mechanism was studied. HCS was undertaken to detect the nuclear condensation, mitochondrial membrane potential, cell permeability, and the release...

Full description

Bibliographic Details
Main Authors: Ibrahim, Mohamed Yousif, Mohd. Hashim, Najihah, Mohan, Syam Morali, Abdulla, Mahmood Ameen, Kamalidehghan, Behnam, Ghaderian, Mostafa, Dehghan, Firouzeh, Ali, Landa Zeenelabdin, Arbab, Ismail Adam, Yahayu, Maizatulakmal, Lian, Gwendoline Ee Cheng, Ahmadipour, Fatemeh, Mohd. Ohd Ali, Hapipah
Format: Article
Language:English
Published: Dove Medical Press Ltd. 2014
Subjects:
Online Access:http://eprints.utm.my/51751/1/SyamMorhan2014_AlphaMangostinFromCratoxylumArborescens.pdf