Determination of structure of precursor of ibuprofen: purification and analysis

(S)-2-(p-isobutylphenyl) propanoic acid, so called ibuprofen, is one of the most popular anti-inflammatory agents. An efficient cross-coupling reaction of organozinc compound of ethyl 2-bromoacrylate, prepared by the reaction of hightly reactive zinc was carried out with aryl iodide to synthesize 2-...

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Bibliographic Details
Main Authors: Abdul Jalil, Aishah, Kurono, Nobuhito, Tokuda, Masao
Format: Conference or Workshop Item
Language:English
Published: 2004
Subjects:
Online Access:http://eprints.utm.my/5240/1/AishahAbdulJalil2004_DeterminationOfStructureOfPrecursorOfIbuprofen.pdf