Global metabolic network reorganization by adaptive mutations allows fast growth of Escherichia coli on glycerol
Comparative whole-genome sequencing enables the identification of specific mutations during adaptation of bacteria to new environments and allelic replacement can establish their causality. However, the mechanisms of action are hard to decipher and little has been achieved for epistatic mutations, e...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2014
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| Subjects: | |
| Online Access: | http://eprints.utm.my/52981/1/ChengKianKai2014_GlobalMetabolicNetworkReorganizationbyAdaptive.pdf |