Model-aided anaerobic metabolic gene knockout of malate dehydrogenase (mdh) gene predicts increased succinate production in Escherichia coli
Succinic acid is considers to be a platform chemical with divergent applications as a precursor for syntheses of commodity and specialty chemicals. Its biobased production could be a green technology when produced by microbial fermentation using Escherichia coli as a chassis host. Metabolic eng...
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2015
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