Molecular dynamic simulation of V176G mutation associated with Gerstmann–Sträussler–Scheinker at elevated temperature
The transformation of cellular prion protein (PrPc) into pathogenic conformer (PrPSc) in transmissible spongiform encephalopathy is expedited by mutations in the prion protein. One recently reported novel mutation V176G is located in region of the protein known to cause Creutzfeldt-Jakob disease (CJ...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Penerbit UTM Press
2016
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| Online Access: | http://eprints.utm.my/70013/1/AshrafFadilJomah2016_MolecularDynamicSimulationOfV176GMutation.pdf |