Identifying significant metabolic pathways using multi-block partial least-squares analysis

In metabolomics, identification of metabolic pathways altered by disease, genetics, or environmental perturbations is crucial to uncover the underlying biological mechanisms. A number of pathway analysis methods are currently available, which are generally based on equal-probability, topological-cen...

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Bibliographic Details
Main Authors: Deng, Lingli, Guo, Fanjing, Cheng, Kian-Kai, Zhu, Jiangjiang, Gu, Haiwei, Raftery, Daniel, Dong, Jiyang
Format: Article
Published: American Chemical Society 2020
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