Optimization of the antioxidant-rich xanthone extract from mangosteen (Garcinia mangostana L.) pericarp via microwave-assisted extraction

Total phenolic content (TPC) and antioxidant properties of xanthone extract from mangosteen pericarp via microwave-assisted extraction (MAE) method was optimized by response surface methodology (RSM). The MAE extraction conditions to obtain optimum antioxidant-rich xanthone extract were at 2.24 min...

Full description

Bibliographic Details
Main Authors: Mohammad, Nor Azizah, Abang Zaidel, Dayang Norulfairuz, Muhamad, Ida Idayu, Abdul Hamid, Mariani, Yaakob, Harisun, Mohd. Jusoh, Yanti Maslina
Format: Article
Language:English
Published: Elsevier Ltd 2019
Subjects:
Online Access:http://eprints.utm.my/87598/1/DayangNorulfairuzAbangZaidel2019_OptimizationoftheAntioxidant-RichXanthoneExtract.pdf
_version_ 1796864473650167808
author Mohammad, Nor Azizah
Abang Zaidel, Dayang Norulfairuz
Muhamad, Ida Idayu
Abdul Hamid, Mariani
Yaakob, Harisun
Mohd. Jusoh, Yanti Maslina
author_facet Mohammad, Nor Azizah
Abang Zaidel, Dayang Norulfairuz
Muhamad, Ida Idayu
Abdul Hamid, Mariani
Yaakob, Harisun
Mohd. Jusoh, Yanti Maslina
author_sort Mohammad, Nor Azizah
collection ePrints
description Total phenolic content (TPC) and antioxidant properties of xanthone extract from mangosteen pericarp via microwave-assisted extraction (MAE) method was optimized by response surface methodology (RSM). The MAE extraction conditions to obtain optimum antioxidant-rich xanthone extract were at 2.24 min of irradiation time, 25 mL/g of solvent-to-solid ratio and 71% of ethanol concentration. The predicted results for four responses were as follows; 320.31 mg gallic acid equivalent/g extract, 83.63% and 93.77% inhibition (DPPH (2,2-diphenyl-1-picrylhydrazyl) and ABTS (2,2′-Azino-bis-3-ethylbenzthiazoline-6-sulfonic acid) assays), and 144.56 mg Trolox equivalent/g extract (FRAP, Ferric reducing antioxidant power). The predicted and actual values were statistically insignificant (P > 0.05). Therefore, these results confirmed that the examined model was acceptable and relevant. MAE led to a slightly similar antioxidant capacity and a higher extraction of α-mangostin, a major xanthone of mangosteen pericarp as compared to water bath-maceration technique.
first_indexed 2024-03-05T20:42:24Z
format Article
id utm.eprints-87598
institution Universiti Teknologi Malaysia - ePrints
language English
last_indexed 2024-03-05T20:42:24Z
publishDate 2019
publisher Elsevier Ltd
record_format dspace
spelling utm.eprints-875982020-11-30T09:04:16Z http://eprints.utm.my/87598/ Optimization of the antioxidant-rich xanthone extract from mangosteen (Garcinia mangostana L.) pericarp via microwave-assisted extraction Mohammad, Nor Azizah Abang Zaidel, Dayang Norulfairuz Muhamad, Ida Idayu Abdul Hamid, Mariani Yaakob, Harisun Mohd. Jusoh, Yanti Maslina TP Chemical technology Total phenolic content (TPC) and antioxidant properties of xanthone extract from mangosteen pericarp via microwave-assisted extraction (MAE) method was optimized by response surface methodology (RSM). The MAE extraction conditions to obtain optimum antioxidant-rich xanthone extract were at 2.24 min of irradiation time, 25 mL/g of solvent-to-solid ratio and 71% of ethanol concentration. The predicted results for four responses were as follows; 320.31 mg gallic acid equivalent/g extract, 83.63% and 93.77% inhibition (DPPH (2,2-diphenyl-1-picrylhydrazyl) and ABTS (2,2′-Azino-bis-3-ethylbenzthiazoline-6-sulfonic acid) assays), and 144.56 mg Trolox equivalent/g extract (FRAP, Ferric reducing antioxidant power). The predicted and actual values were statistically insignificant (P > 0.05). Therefore, these results confirmed that the examined model was acceptable and relevant. MAE led to a slightly similar antioxidant capacity and a higher extraction of α-mangostin, a major xanthone of mangosteen pericarp as compared to water bath-maceration technique. Elsevier Ltd 2019-10 Article PeerReviewed application/pdf en http://eprints.utm.my/87598/1/DayangNorulfairuzAbangZaidel2019_OptimizationoftheAntioxidant-RichXanthoneExtract.pdf Mohammad, Nor Azizah and Abang Zaidel, Dayang Norulfairuz and Muhamad, Ida Idayu and Abdul Hamid, Mariani and Yaakob, Harisun and Mohd. Jusoh, Yanti Maslina (2019) Optimization of the antioxidant-rich xanthone extract from mangosteen (Garcinia mangostana L.) pericarp via microwave-assisted extraction. Heliyon, 5 (10). e02571-e02571. ISSN 2405-8440 http://dx.doi.org/10.1016/j.heliyon.2019.e02571
spellingShingle TP Chemical technology
Mohammad, Nor Azizah
Abang Zaidel, Dayang Norulfairuz
Muhamad, Ida Idayu
Abdul Hamid, Mariani
Yaakob, Harisun
Mohd. Jusoh, Yanti Maslina
Optimization of the antioxidant-rich xanthone extract from mangosteen (Garcinia mangostana L.) pericarp via microwave-assisted extraction
title Optimization of the antioxidant-rich xanthone extract from mangosteen (Garcinia mangostana L.) pericarp via microwave-assisted extraction
title_full Optimization of the antioxidant-rich xanthone extract from mangosteen (Garcinia mangostana L.) pericarp via microwave-assisted extraction
title_fullStr Optimization of the antioxidant-rich xanthone extract from mangosteen (Garcinia mangostana L.) pericarp via microwave-assisted extraction
title_full_unstemmed Optimization of the antioxidant-rich xanthone extract from mangosteen (Garcinia mangostana L.) pericarp via microwave-assisted extraction
title_short Optimization of the antioxidant-rich xanthone extract from mangosteen (Garcinia mangostana L.) pericarp via microwave-assisted extraction
title_sort optimization of the antioxidant rich xanthone extract from mangosteen garcinia mangostana l pericarp via microwave assisted extraction
topic TP Chemical technology
url http://eprints.utm.my/87598/1/DayangNorulfairuzAbangZaidel2019_OptimizationoftheAntioxidant-RichXanthoneExtract.pdf
work_keys_str_mv AT mohammadnorazizah optimizationoftheantioxidantrichxanthoneextractfrommangosteengarciniamangostanalpericarpviamicrowaveassistedextraction
AT abangzaideldayangnorulfairuz optimizationoftheantioxidantrichxanthoneextractfrommangosteengarciniamangostanalpericarpviamicrowaveassistedextraction
AT muhamadidaidayu optimizationoftheantioxidantrichxanthoneextractfrommangosteengarciniamangostanalpericarpviamicrowaveassistedextraction
AT abdulhamidmariani optimizationoftheantioxidantrichxanthoneextractfrommangosteengarciniamangostanalpericarpviamicrowaveassistedextraction
AT yaakobharisun optimizationoftheantioxidantrichxanthoneextractfrommangosteengarciniamangostanalpericarpviamicrowaveassistedextraction
AT mohdjusohyantimaslina optimizationoftheantioxidantrichxanthoneextractfrommangosteengarciniamangostanalpericarpviamicrowaveassistedextraction