Immunotherapeutic implications of negative regulation by protein tyrosine phosphatases in T cells: the emerging cases of PTP1B and TCPTP
In the context of inflammation, T cell activation occurs by the concerted signals of the T cell receptor (TCR), co-stimulatory receptors ligation, and a pro-inflammatory cytokine microenvironment. Fine-tuning these signals is crucial to maintain T cell homeostasis and prevent self-reactivity while o...
| Autores principales: | , , |
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| Formato: | Artículo |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2024-04-01
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| Colección: | Frontiers in Medicine |
| Materias: | |
| Acceso en línea: | https://www.frontiersin.org/articles/10.3389/fmed.2024.1364778/full |