Understanding Epistatic Interactions between Genes Targeted by Non-coding Regulatory Elements in Complex Diseases
Genome-wide association studies have proven the highly polygenic architecture of complex diseases or traits; therefore, single-locus-based methods are usually unable to detect all involved loci, especially when individual loci exert small effects. Moreover, the majority of associated single-nucleoti...
| Main Authors: | , , |
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| 格式: | Article |
| 語言: | English |
| 出版: |
BioMed Central
2014-12-01
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| 叢編: | Genomics & Informatics |
| 主題: | |
| 在線閱讀: | http://genominfo.org/upload/pdf/gni-12-181.pdf |