Interim data monitoring to enroll higher-risk participants in HIV prevention trials

<p>Abstract</p> <p>Background</p> <p>Lower-than-expected incidence of HIV undermines sample size calculations and compromises the power of a HIV prevention trial. We evaluated the effectiveness of interim monitoring of HIV infection rates and on-going modification of re...

Descrizione completa

Dettagli Bibliografici
Autori principali: Umo-Otong John, Otusanya Sakiru, Ogunsola Folasade, Obunge Orikomaba, Halpern Vera, Wang Chin-Hua, Mehta Neha
Natura: Articolo
Lingua:English
Pubblicazione: BMC 2009-06-01
Serie:BMC Medical Research Methodology
Accesso online:http://www.biomedcentral.com/1471-2288/9/44