Engineering of a DNA/γPNA Hybrid Nanoreporter for ctDNA Mutation Detection via γPNA Urinalysis

Engineering of a DNA/γPNA Hybrid Nanoreporter for ctDNA Mutation Detection via γPNA Urinalysis

Abstract Detection of circulating tumor DNA (ctDNA) mutations, which are molecular biomarkers present in bodily fluids of cancer patients, can be applied for tumor diagnosis and prognosis monitoring. However, current profiling of ctDNA mutations relies primarily on polymerase chain reaction (PCR) an...

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Bibliographic Details
Main Authors: Zhichu Xiang, Jianhua Lu, Yang Ming, Weisheng Guo, Xiaoyuan Chen, Weijian Sun
Format: Article
Language:English
Published: Wiley 2024-09-01
Series:Advanced Science
Subjects:
ctDNA mutation
tumor detection
urinalysis
γPNA
Online Access:https://doi.org/10.1002/advs.202310225

Internet

https://doi.org/10.1002/advs.202310225

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