Abundant CpG-sequences in human genomes inhibit KIR3DL2-expressing NK cells

Killer Immunoglobulin-like Receptors (KIR) comprise a diverse, highly polymorphic family of cell-surface glycoproteins that are principally expressed by Natural Killer (NK) cells. These innate immune lymphocytes fulfill vital functions in human reproduction and immune responses to viral infection. K...

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Bibliographic Details
Main Authors: Jason Pugh, Lisbeth Guethlein, Peter Parham
Format: Article
Language:English
Published: PeerJ Inc. 2021-11-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/12258.pdf