miR-100 induces epithelial-mesenchymal transition but suppresses tumorigenesis, migration and invasion.
Whether epithelial-mesenchymal transition (EMT) is always linked to increased tumorigenicity is controversial. Through microRNA (miRNA) expression profiling of mammary epithelial cells overexpressing Twist, Snail or ZEB1, we identified miR-100 as a novel EMT inducer. Surprisingly, miR-100 inhibits t...
| Hlavní autoři: | , , , , , , , , , , , , |
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| Médium: | Článek |
| Jazyk: | English |
| Vydáno: |
Public Library of Science (PLoS)
2014-02-01
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| Edice: | PLoS Genetics |
| On-line přístup: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1004177&type=printable |