Axon demyelination and degeneration in a zebrafish spastizin model of hereditary spastic paraplegia

Axon demyelination and degeneration in a zebrafish spastizin model of hereditary spastic paraplegia

Hereditary spastic paraplegias (HSPs) are a diverse set of neurological disorders characterized by progressive spasticity and weakness in the lower limbs caused by damage to the axons of the corticospinal tract. More than 88 genetic mutations have been associated with HSP, yet the mechanisms underly...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Vranda Garg, Selina André, Luisa Heyer, Gudrun Kracht, Torben Ruhwedel, Patricia Scholz, Till Ischebeck, Hauke B. Werner, Christian Dullin, Jacob Engelmann, Wiebke Möbius, Martin C. Göpfert, Roland Dosch, Bart R. H. Geurten
स्वरूप: लेख
भाषा:English
प्रकाशित: The Royal Society 2024-11-01
श्रृंखला:Open Biology
विषय:
Hereditary spastic paraplegia (HSP)
spastizin
zebrafish
lower limb spasticity
mauthner neurons
C-start escape response
ऑनलाइन पहुंच:https://royalsocietypublishing.org/doi/10.1098/rsob.240100

इंटरनेट

https://royalsocietypublishing.org/doi/10.1098/rsob.240100

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