Gene expression changes in sickle cell reticulocytes and their clinical associations

Gene expression changes in sickle cell reticulocytes and their clinical associations

Abstract Transcriptional changes in compensatory erythropoiesis in sickle cell anemia (SCA) and their disease modulation are unclear. We detected 1226 differentially expressed genes in hemoglobin SS reticulocytes compared to non-anemic hemoglobin AA controls. Assessing developmental expression chang...

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Detalhes bibliográficos
Principais autores: Xu Zhang, Jihyun Song, Binal N. Shah, Jin Han, Taif Hassan, Galina Miasniakova, Adelina Sergueeva, Sergei Nekhai, Roberto F. Machado, Mark T. Gladwin, Santosh L. Saraf, Josef T. Prchal, Victor R. Gordeuk
Formato: Artigo
Idioma:English
Publicado em: Nature Portfolio 2023-08-01
coleção:Scientific Reports
Acesso em linha:https://doi.org/10.1038/s41598-023-40039-2

Internet

https://doi.org/10.1038/s41598-023-40039-2

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