Inherited salt-losing tubulopathies are associated with immunodeficiency due to impaired IL-17 responses
Salt levels in culture affect the polarisation of Th17 cells, which normally protect the host from fungal and bacterial infections. Here, the authors study patients with salt-losing tubulopathies (SLT) to find that, while Th17 immunity is dampened in SLT patients, their Th17-inducing signaling pathw...
| मुख्य लेखकों: | , , , , , , , , , , |
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| स्वरूप: | लेख |
| भाषा: | English |
| प्रकाशित: |
Nature Portfolio
2020-08-01
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| श्रृंखला: | Nature Communications |
| ऑनलाइन पहुंच: | https://doi.org/10.1038/s41467-020-18184-3 |