DJ-1 Proteoforms in Breast Cancer Cells: The Escape of Metabolic Epigenetic Misregulation

DJ-1 Proteoforms in Breast Cancer Cells: The Escape of Metabolic Epigenetic Misregulation

Enhanced glycolysis is a hallmark of breast cancer. In cancer cells, the high glycolytic flux induces carbonyl stress, a damaging condition in which the increase of reactive carbonyl species makes DNA, proteins, and lipids more susceptible to glycation. Together with glucose, methylglyoxal (MGO), a...

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Dettagli Bibliografici
Autori principali:	Domenica Scumaci, Erika Olivo, Claudia Vincenza Fiumara, Marina La Chimia, Maria Teresa De Angelis, Sabrina Mauro, Giosuè Costa, Francesca Alessandra Ambrosio, Stefano Alcaro, Valter Agosti, Francesco Saverio Costanzo, Giovanni Cuda
Natura:	Articolo
Lingua:	English
Pubblicazione:	MDPI AG 2020-08-01
Serie:	Cells
Soggetti:	metabolic rewiring DJ-1 AGEs Akt breast cancer histones
Accesso online:	https://www.mdpi.com/2073-4409/9/9/1968

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