DJ-1 Proteoforms in Breast Cancer Cells: The Escape of Metabolic Epigenetic Misregulation

DJ-1 Proteoforms in Breast Cancer Cells: The Escape of Metabolic Epigenetic Misregulation

Enhanced glycolysis is a hallmark of breast cancer. In cancer cells, the high glycolytic flux induces carbonyl stress, a damaging condition in which the increase of reactive carbonyl species makes DNA, proteins, and lipids more susceptible to glycation. Together with glucose, methylglyoxal (MGO), a...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Domenica Scumaci, Erika Olivo, Claudia Vincenza Fiumara, Marina La Chimia, Maria Teresa De Angelis, Sabrina Mauro, Giosuè Costa, Francesca Alessandra Ambrosio, Stefano Alcaro, Valter Agosti, Francesco Saverio Costanzo, Giovanni Cuda
स्वरूप: लेख
भाषा:English
प्रकाशित: MDPI AG 2020-08-01
श्रृंखला:Cells
विषय:
metabolic rewiring
DJ-1
AGEs
Akt
breast cancer
histones
ऑनलाइन पहुंच:https://www.mdpi.com/2073-4409/9/9/1968

इंटरनेट

https://www.mdpi.com/2073-4409/9/9/1968

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