Examination of MARCO activity on dendritic cell phenotype and function using a gene knockout mouse.
We have reported the upregulation of MARCO, a member of the class A scavenger receptor family, on the surface of murine and human dendritic cells (DCs) pulsed with tumor lysates. Exposure of murine tumor lysate-pulsed DCs to an anti-MARCO antibody led to loss of dendritic-like processes and enhanced...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Jezik: | English |
| Izdano: |
Public Library of Science (PLoS)
2013-01-01
|
| Serija: | PLoS ONE |
| Online dostop: | http://europepmc.org/articles/PMC3698187?pdf=render |