Sex-dependent transcription of cardiac electrophysiology and links to acetylation modifiers based on the GTEx database

Development of safer drugs based on epigenetic modifiers, e.g., histone deacetylase inhibitors (HDACi), requires better understanding of their effects on cardiac electrophysiology. Using RNAseq data from the genotype-tissue-expression database (GTEx), we created models that link the abundance of ace...

Descrición completa

Detalles Bibliográficos
Main Authors: Michael P. Pressler, Anelia Horvath, Emilia Entcheva
Formato: Artigo
Idioma:English
Publicado: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Acceso en liña:https://www.frontiersin.org/articles/10.3389/fcvm.2022.941890/full