Regional covariance of white matter hyperintensity volume patterns associated with hippocampal volume in healthy aging

Regional covariance of white matter hyperintensity volume patterns associated with hippocampal volume in healthy aging

Hippocampal volume is particularly sensitive to the accumulation of total brain white matter hyperintensity volume (WMH) in aging, but how the regional distribution of WMH volume differentially impacts the hippocampus has been less studied. In a cohort of 194 healthy older adults ages 50–89, we used...

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Detalhes bibliográficos
Principais autores: Emily J. Van Etten, Pradyumna K. Bharadwaj, Matthew D. Grilli, David A. Raichlen, Georg A. Hishaw, Matthew J. Huentelman, Theodore P. Trouard, Gene E. Alexander
Formato: Artigo
Idioma:English
Publicado em: Frontiers Media S.A. 2024-03-01
coleção:Frontiers in Aging Neuroscience
Assuntos:
regional white matter hyperintensity volume
hippocampal volume
brain aging
subjective memory complaints
scaled subprofile model
multivariate analyses
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fnagi.2024.1349449/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2024.1349449/full

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