Distal regulatory elements identified by methylation and hydroxymethylation haplotype blocks from mouse brain

Abstract Background 5-Hydroxymethylcytosine (5hmC) is an oxidation product of 5-methylcytosine (5mC), and adjacent CpG sites in mammalian genome can be co-methylated and co-hydroxymethylated due to the processivity of DNMT and TET enzymes. Results We applied TAB-seq and oxBS-seq to selectively detec...

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Manylion Llyfryddiaeth
Prif Awduron: Qin Ma, Zhengzheng Xu, Huan Lu, Ziying Xu, Yuanyuan Zhou, Bifeng Yuan, Weimin Ci
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: BMC 2018-12-01
Cyfres:Epigenetics & Chromatin
Pynciau:
Mynediad Ar-lein:http://link.springer.com/article/10.1186/s13072-018-0248-3