Distal regulatory elements identified by methylation and hydroxymethylation haplotype blocks from mouse brain
Abstract Background 5-Hydroxymethylcytosine (5hmC) is an oxidation product of 5-methylcytosine (5mC), and adjacent CpG sites in mammalian genome can be co-methylated and co-hydroxymethylated due to the processivity of DNMT and TET enzymes. Results We applied TAB-seq and oxBS-seq to selectively detec...
| 主要な著者: | , , , , , , |
|---|---|
| フォーマット: | 論文 |
| 言語: | English |
| 出版事項: |
BMC
2018-12-01
|
| シリーズ: | Epigenetics & Chromatin |
| 主題: | |
| オンライン･アクセス: | http://link.springer.com/article/10.1186/s13072-018-0248-3 |