Compensatory cross-talk between autophagy and glycolysis regulates senescence and stemness in heterogeneous glioblastoma tumor subpopulations

Abstract Despite tremendous research efforts, successful targeting of aberrant tumor metabolism in clinical practice has remained elusive. Tumor heterogeneity and plasticity may play a role in the clinical failure of metabolism-targeting interventions for treating cancer patients. Moreover, compensa...

詳細記述

書誌詳細
主要な著者: Emma Martell, Helgi Kuzmychova, Harshal Senthil, Esha Kaul, Chirayu R. Chokshi, Chitra Venugopal, Christopher M. Anderson, Sheila K. Singh, Tanveer Sharif
フォーマット: 論文
言語:English
出版事項: BMC 2023-07-01
シリーズ:Acta Neuropathologica Communications
主題:
オンライン・アクセス:https://doi.org/10.1186/s40478-023-01604-y