Compensatory cross-talk between autophagy and glycolysis regulates senescence and stemness in heterogeneous glioblastoma tumor subpopulations

Compensatory cross-talk between autophagy and glycolysis regulates senescence and stemness in heterogeneous glioblastoma tumor subpopulations

Abstract Despite tremendous research efforts, successful targeting of aberrant tumor metabolism in clinical practice has remained elusive. Tumor heterogeneity and plasticity may play a role in the clinical failure of metabolism-targeting interventions for treating cancer patients. Moreover, compensa...

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Detaylı Bibliyografya
Asıl Yazarlar: Emma Martell, Helgi Kuzmychova, Harshal Senthil, Esha Kaul, Chirayu R. Chokshi, Chitra Venugopal, Christopher M. Anderson, Sheila K. Singh, Tanveer Sharif
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: BMC 2023-07-01
Seri Bilgileri:Acta Neuropathologica Communications
Konular:
Glioblastoma
Tumor heterogeneity
Cancer stem cell-like cells
Metabolism
Glycolysis
Autophagy
Online Erişim:https://doi.org/10.1186/s40478-023-01604-y

Internet

https://doi.org/10.1186/s40478-023-01604-y

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