Ovarian cancer ascites induces skeletal muscle wasting in vitro and reflects sarcopenia in patients

Ovarian cancer ascites induces skeletal muscle wasting in vitro and reflects sarcopenia in patients

Abstract Background Cachexia‐associated skeletal muscle wasting or ‘sarcopenia’ is highly prevalent in ovarian cancer and contributes to poor outcome. Drivers of cachexia‐associated sarcopenia in ovarian cancer remain elusive, underscoring the need for novel and better models to identify tumour fact...

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Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Jorne Ubachs, Wouter R.P.H. van deWorp, Rianne D.W. Vaes, Kenneth Pasmans, Ramon C. Langen, Ruth C.R. Meex, Annemarie A.J.H.M. vanBijnen, Sandrina Lambrechts, Toon Van Gorp, Roy F.P.M. Kruitwagen, Steven W.M. Olde Damink, Sander S. Rensen
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: Wiley 2022-02-01
Цуврал:Journal of Cachexia, Sarcopenia and Muscle
Нөхцлүүд:
Protein synthesis
Protein breakdown
Atrogenes
NF‐κB
Interleukin‐6
C2C12 cells
Онлайн хандалт:https://doi.org/10.1002/jcsm.12885

Интернэт

https://doi.org/10.1002/jcsm.12885

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