RPGR is a guanine nucleotide exchange factor for the small GTPase RAB37 required for retinal function via autophagy regulation
Summary: Although the small GTPase RAB37 acts as an organizer of autophagosome biogenesis, the upstream regulatory mechanism of autophagy via guanosine diphosphate (GDP)-guanosine triphosphate (GTP) exchange in maintaining retinal function has not been determined. We found that retinitis pigmentosa...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Sprog: | English |
Udgivet: |
Elsevier
2024-04-01
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Serier: | Cell Reports |
Fag: | |
Online adgang: | http://www.sciencedirect.com/science/article/pii/S2211124724003383 |