Proximal tubular RAGE mediated the renal fibrosis in UUO model mice via upregulation of autophagy
Abstract Previous studies reported that RAGE participated in the process of kidney fibrosis, but the function and regulation pathway of RAGE in proximal tubular cells in this process remains unclear. Here, we found that expression of RAGE was increased by TGF-β1 treatment and unilateral ureteral obs...
Главные авторы: | Bohao Liu, Tianshi Sun, Huiling Li, Shuangfa Qiu, Yijian Li, Dongshan Zhang |
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Формат: | Статья |
Язык: | English |
Опубликовано: |
Nature Publishing Group
2022-04-01
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Серии: | Cell Death and Disease |
Online-ссылка: | https://doi.org/10.1038/s41419-022-04856-z |
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