Simvastatin-Loaded Nanostructured Lipid Carriers as Topical Drug Delivery System for Wound Healing Purposes: Preparation, Characterization, and In Vivo Histopathological Studies

Simvastatin-Loaded Nanostructured Lipid Carriers as Topical Drug Delivery System for Wound Healing Purposes: Preparation, Characterization, and In Vivo Histopathological Studies

Purpose: Simvastatin, a 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, is a commonly used drug to reduce total cholesterol and low-density lipoprotein (LDL) levels. Furthermore, several mechanisms showed the wound-healing potential of statins, especially simvastatin. Simvastati...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Seyedeh Maryam Mousavi-Simakani, Amir Azadi, Nader Tanideh, Navid Omidifar, Parisa Ghasemiyeh, Soliman Mohammadi-Samani
Format: Artikel
Sprache:English
Veröffentlicht: Tabriz University of Medical Sciences 2023-11-01
Schriftenreihe:Advanced Pharmaceutical Bulletin
Schlagworte:
simvastatin
nanostructured lipid carriers
topical drug delivery systems
histopathological studies
wound healing
Online Zugang:https://apb.tbzmed.ac.ir/PDF/apb-13-761.pdf

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