Transmission of tauopathy strains is independent of their isoform composition
Although normal human brains express 6 tau isoforms in equal ratio with 3 or 4 microtubule-binding repeat domains (3R and 4R), tau inclusions from different human tauopathy brains, now considered as different strains, have distinct isoform compositions and strain properties and the relationship betw...
| Main Authors: | , , , , , , , , , , , , |
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| 格式: | 文件 |
| 语言: | English |
| 出版: |
Nature Portfolio
2020-01-01
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| 丛编: | Nature Communications |
| 在线阅读: | https://doi.org/10.1038/s41467-019-13787-x |