Novel p53 therapies for head and neck cancer

Inactivation of the tumor suppressor p53 is the predominant pathogenetic event in head and neck squamous cell carcinoma (HNSCC). The p53 pathway in HNSCC can be compromised through multiple mechanisms including gene mutations, hyperactivation of endogenous negative p53 regulators and by the human pa...

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書目詳細資料
Main Authors: Mario R. Castellanos, Quintin Pan
格式: Article
語言:English
出版: Wiley 2016-06-01
叢編:World Journal of Otorhinolaryngology-Head and Neck Surgery
在線閱讀:http://www.sciencedirect.com/science/article/pii/S2095881116300142