Metformin Ameliorates Chronic Colitis-Related Intestinal Fibrosis via Inhibiting TGF-β1/Smad3 Signaling

Intestinal fibrosis is considered to be a chronic complication of inflammatory bowel disease (IBD) and seriously threatening human health. Effective medical therapies or preventive measures are desirable but currently unavailable. Metformin has been proved to have a satisfactory anti-inflammatory ef...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Ying Wang, Zhi Wang, Huiping Yang, Shuze Chen, Dekai Zheng, Xiuying Liu, Qinrui Jiang, Ye Chen
التنسيق: مقال
اللغة:English
منشور في: Frontiers Media S.A. 2022-05-01
سلاسل:Frontiers in Pharmacology
الموضوعات:
الوصول للمادة أونلاين:https://www.frontiersin.org/articles/10.3389/fphar.2022.887497/full