Switching imidazole reactivity by dynamic control of tautomer state in an allosteric foldamer
Abstract Molecular biology achieves control over complex reaction networks by means of molecular systems that translate a chemical input (such as ligand binding) into an orthogonal chemical output (such as acylation or phosphorylation). We present an artificial molecular translation device that conv...
| Main Authors: | , , , |
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| 格式: | 文件 |
| 语言: | English |
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Nature Portfolio
2023-05-01
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| 丛编: | Nature Communications |
| 在线阅读: | https://doi.org/10.1038/s41467-023-38339-2 |