The temporal association of CapZ with early endosomes regulates endosomal trafficking and viral entry into host cells

Abstract Background Many viruses enter host cells by hijacking endosomal trafficking. CapZ, a canonical actin capping protein, participates in endosomal trafficking, yet its precise role in endocytosis and virus infection remains elusive. Results Here, we showed that CapZ was transiently associated...

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Bibliographic Details
Main Authors: Huazhang Zhu, Dawei Wang, Zuodong Ye, Lihong Huang, Wenjie Wei, Kui Ming Chan, Rongxin Zhang, Liang Zhang, Jianbo Yue
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Biology
Subjects:
Online Access:https://doi.org/10.1186/s12915-024-01819-y