Differential blood transcriptome modules predict response to corticosteroid therapy in alcoholic hepatitis

Differential blood transcriptome modules predict response to corticosteroid therapy in alcoholic hepatitis

Background & Aims: In patients with severe alcoholic hepatitis (SAH), little is known about the profile of peripheral blood mononuclear cells (PBMCs) at baseline and during corticosteroid therapy, among those who can be treated successfully with steroids (steroid-responders [R] and those who...

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Bibliographic Details
Main Authors: Shvetank Sharma, Sukriti Baweja, Jaswinder S. Maras, Saggere M. Shasthry, Richard Moreau, Shiv K. Sarin
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:JHEP Reports
Subjects:
Alcoholic liver disease
Transcriptome
Steroid
Glucocorticoid receptor
NR3C1
Online Access:http://www.sciencedirect.com/science/article/pii/S2589555921000598

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http://www.sciencedirect.com/science/article/pii/S2589555921000598

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