Multiple Myeloma With Amplification of Chr1q: Therapeutic Opportunity and Challenges

Multiple myeloma (MM) is an incurable plasma cell malignancy with a heterogeneous genetic background. Each MM subtype may have its own therapeutic vulnerabilities, and tailored therapy could improve outcomes. However, the cumulative frequency of druggable targets across patients is very low, which h...

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Главные авторы: Romanos Sklavenitis-Pistofidis, Gad Getz, Irene Ghobrial, Maria Papaioannou
Формат: Статья
Язык:English
Опубликовано: Frontiers Media S.A. 2022-07-01
Серии:Frontiers in Oncology
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Online-ссылка:https://www.frontiersin.org/articles/10.3389/fonc.2022.961421/full