Nanoparticle-mediated selective Sfrp-1 silencing enhances bone density in osteoporotic mice
Abstract Osteoporosis (OP) is characterized by a loss in bone mass and mineral density. The stimulation of the canonical Wnt/β-catenin pathway has been reported to promote bone formation, this pathway is controlled by several regulators as secreted frizzled-related protein-1 (Sfrp-1), antagonist of...
| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado: |
BMC
2022-10-01
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| Series: | Journal of Nanobiotechnology |
| Subjects: | |
| Acceso en liña: | https://doi.org/10.1186/s12951-022-01674-5 |