Iron-sulfur clusters are involved in post-translational arginylation
The enzyme ATE1 catalyzes eukaryotic post-translation arginylation, a key protein modification necessary for cellular homeostasis. Here, the authors show that ATE1s are previously unrealized iron-sulfur proteins that use this oxygen-sensitive inorganic cofactor to control cellular arginylation
| Հիմնական հեղինակներ: | , , , , , , , , , , , |
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| Ձևաչափ: | Հոդված |
| Լեզու: | English |
| Հրապարակվել է: |
Nature Portfolio
2023-01-01
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| Շարք: | Nature Communications |
| Առցանց հասանելիություն: | https://doi.org/10.1038/s41467-023-36158-z |