Zfp57 mutant ES cell lines directly derived from blastocysts

Zfp57 is a master regulator of genomic imprinting in mouse embryos. To further test its functions, we have derived multiple Zfp57 mutant ES clones directly from mouse blastocysts. Indeed, we found DNA methylation imprint was lost at most examined imprinting control regions in these Zfp57 mutant ES c...

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Podrobná bibliografie
Hlavní autoři: Ho-Tak Lau, Lizhi Liu, Xiajun Li
Médium: Článek
Jazyk:English
Vydáno: Elsevier 2016-03-01
Edice:Stem Cell Research
On-line přístup:http://www.sciencedirect.com/science/article/pii/S1873506116000027